Dr. Melfi’s Medicine is a Negroni-sour mashup from Brooks Reitz at Melfi’s in Charleston, South Carolina. It’s a “Negroni for beginners,” as Reitz describes it – a great way to show off the magic of the classic flavor combination, without the heavy hand of an all-spirits mix.
Since Campari is the aperitif of choice in a Negroni, it makes sense to use it (or a similarly-bitter option) here, too. Aperol is much sweeter and gives the drink a candy-like quality that we occasionally enjoy, though we concede that it does miss the point a bit.
